Promising Health Benefits of Hippophae rhamnoides L. (Sea Buckthorn): A Miracle Plant

Authors

  • Madhuri Mehta Department of Zoology, Punjab Agricultural University, Ludhiana, India
  • Vijayta Gupta Department of Chemistry, University of Jammu, Jammu, India
  • Vinay Kant Division of Pharmacology & Toxicology, IVRI, Bareilly, UP, India & Department of Veterinary Pharmacology and Toxicology, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar, Haryana, India
  • Chandresh Varshneya Department of Pharmacology and Toxicology, COVAS, CSKHPKV, Palampur, Himachal Pradesh, India

DOI:

https://doi.org/10.51983/ajsat-2019.8.1.1041

Keywords:

Seabuckthorn, Anti-Cancer, Antioxidant, Anti-Inflammatory

Abstract

Seabuckthorn (Hippophae rhamnoides L.), a spiny bush plant native to Europe and Asia, have many nutritional and medicinal properties. All parts of this plant are rich source of bioactive components such as, tocopherols, carotenoids, flavonoids, vitamins, sugar, organic acids and minerals. Various in vivo and in vitro studies on animals and human suggest that seabuckthorn has many beneficial effects as cardioprotective, antiatherogenic, antioxidant, anticancer, immunomodulatory, anti-bacterial, antiviral and anti-inflammatory, which reveals its medicinal and pharmacological properties. Seabuckthorn can be supplemented as nutraceuticals in animal feed to enhance its antioxidative potential, strengthen the immune system, which may help the organism to resist stress. To promote the large scale utilization of seabuckthorn, it would be worthwhile to perform more research on this plant.

References

I. I. Brekhman, Man and Biologically Active Substances, 1st ed. Oxford, England: Pergamon Press, 1980.

S. Fulder, “The drug that builds Russians,” New Scientist, vol. 88, pp. 576-579, 1980.

P. Scartezzini and E. Speroni, “Review on some plants of Indian traditional medicine with antioxidant activity,” J. Ethanopharmacol., vol. 71, pp. 23-43, 2000.

A. Rousi, “The genus Hippophae L., a taxonomic study,” Ann. Bot. Fenn., vol. 8, pp. 177-227, 1971.

D. Dhyani, R. K. Maikhuri, S. Misra, and K. S. Rao, “Endorsing the declining indigenous ethnobotanical knowledge system of Seabuckthorn in Central Himalaya, India,” J. Ethanopharmacol., vol. 127, pp. 329-34, 2010.

T. Xiaoping, S. Qaiohong, C. Xiaolon, and C. Jun, "Study of biochemical pharmacology of Seabuckthorn fruit oil and its compound health products," in Proc. Int. Workshop on Seabuckthorn, Beijing, 1995, pp. 162-164.

V. K. Yadav, V. K. Sah, A. K. Singh, and S. K. Sharma, “Variations in morphological and biochemical characters of Seabuckthorn (Hippophae salicifolia D. Don.) populations growing in Harsil area of Garhwal Himalaya in India,” Trop. Agric. Res. Ext., vol. 9, pp. 1-7, 2006.

R. Lu, Sea buckthorn: A multipurpose plant species for fragile mountains, International Centre for Integrated Mountain Development, Karmandu, Nepal, 1992.

V. Singh, "Seabuckthorn (Hippophae L.) in traditional medicines," in Seabuckthorn (Hippophae L.): A Multipurpose Wonder Plant, New Delhi, India: Daya Publishing House, 2005, vol. 2, pp. 505-521.

L. H. Shi, H. J. Cai, X. Y. Chen, and C. M. Yang, “Study on the Antioxidation effect of Hippophae rhamnoides L. seed oil,” Acta Nutrimenta Sinica, vol. 3, pp. 292-295, 1994.

Y. B. Ji and Y. Gao, “Effect of feeding sea buckthorn seed oil and sea buckthorn seed oil supplemented with sodium selenite in vivo on structural stability of erythrocyte ghosts in rats,” J. Biol. Chem., vol. 7, pp. 441-446, 1991.

B. Yang et al., “Effects of dietary supplementation with sea buckthorn (Hippophae rhamnoides L.) seed and pulp oils on atopic dermatitis,” J. Nutr. Biochem., vol.10, pp. 622-630, 1999.

J. Xing et al., “Effects of sea buckthorn (Hippophae rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats,” Fitoterapia, vol. 73, pp. 644-650, 2002.

M. Spansu et al., “Effect of different treatment schedules with “Polivitarom” (Hippophae rhamnoides extracts) and humoral and cellular immune response in rabbits,” MedivinoVeterinaria, vol. 48, pp. 281-288, 1994.

S. Geetha et al., “Evaluation of antioxidant activity of leaf extract of Sea buckthorn (Hippophae rhamnoides L.) on chromium (VI) induced oxidative stress in male albino rats,” J. Ethanopharmacol., vol. 87, pp. 247-251, 2003.

W. Zhang, J. Yan, J. Duo, B. Ren, and J. Guo, "Preliminary study of biochemical constitutions of berry of sea buckthorn growing in Shanxi province and their changing trend," in Proc. Int. Symp. Sea Buckthorn (H. rhamnoides L.), Xian, China, 1989, pp. 96−105.

T. Cheng et al., “Acute toxicity of flesh oil of Hippophaerhamnoides L. and its protection against experimental hepatic injury,” Zhongguo Zhong Yao Za Zhi, vol. 15, pp. 45-47, 1990.

X. Yaonian et al., "A study of the compositions of seabuckthorn oils in China," in Proc. Int. Workshop on Seabuckthorn, Beijing, 1995.

A. Zeb, “Important therapeutic uses of Sea buckthorn (Hippophae): a review,” J. Biol. Sci., vol. 4, pp. 687-693, 2004.

H. M. Leskinen et al., "Regioisomer compositions of vaccenic and oleic acid containing triacylglycerols in sea buckthorn (Hippophae rhamnoides) pulp oils: influence of origin and weather conditions," J. Agric. Food Chem., vol. 58, pp. 537-545, 2010.

B. R. Yang, "Lipophilic components of sea buckthorn (Hippophaėrhamnoides) seeds and berries and physiological effects of sea buckthorn oils," PhD thesis, Turku University, Finland, 2001.

H. Kallio, B. Yang, and P. Peippo, “Effects of different origins and harvesting time on vitamin C, tocopherols and tocotrienols in Sea buckthorn (Hippophae rhamnoides L.) berries,” J. Agric. Food Chem., vol. 50, pp. 6136-6142, 2002.

S. C. Andersson et al., “Carotenoids in sea buckthorn (Hippophae rhamnoides L.) berries during ripening and use of pheophytin a as a maturity marker,” J. Agric. Food Chem., vol. 57, pp. 250-258, 2009.

B. Yang and H. P. Kallio, “Fatty acid composition of lipids in Sea buckthorn (Hippophae rhamnoides L.) berries of different origins,” J. Agric. Food Chem., vol. 49, pp. 1939-1947, 2001.

R. K. Gupta and V. Singh, "Mineral composition of Seabuckthorn (Hippophae L.)," in Seabuckthorn (Hippophae L.): A Multipurpose Wonder Plant, New Delhi, India: Daya Publishing House, 2005, vol. 2, pp. 272-284.

A. S. Chauhan et al., “Preparation and quality evaluation of processed products from sea buckthorn (Hippophaė rhamnoides Lin.) berries,” Beverage Food World, vol. 1, pp. 31−34, 2001.

S. Geetha et al., “Antioxidant and immunomodulatory properties of Sea buckthorn (Hippophae rhamnoides) – an in vitro study,” J. Ethanopharmacol., vol. 79, pp. 373-378, 2002.

S. Geetha et al., “Immunomodulatory effects of seabuckthorn (Hippophae rhamnoides L.) against chromium (VI) induced immunosuppression,” Mol. Cell. Biochem., vol. 278, pp. 101-109, 2005.

K. P. Mishra et al., “A comparative analysis of immunomodulatory potential of Seabuckthorn leaf extract in young and old mice,” Biomed. Aging Pathol., vol. 1, pp. 61-64, 2011.

T. Ramasamy, C. Varshneya, and V. C. Katoch, "Immunoprotective effect of Seabuckthorn (Hippophae rhamnoides) and Glucomannan on T-2 toxin-induced immunodepression in poultry," Vet. Med. Int., 6 pages, 2010, DOI: 10.4061/2010/149373.

S. Narayanan et al., “Antioxidant activities of seabuckthorn (Hippophae rhamnoides) during hypoxia induced oxidative stress in glial cells,” Mol. Cell. Biochem., vol. 278, pp. 9-14, 2005.

C. Varshneya, V. Kant, and M. Mehta, “Total phenolic contents and free radical scavenging activities of different extracts of seabuckthorn (Hippophae rhamnoides) pomace without seeds,” Int. J. Food Sci. Nutr., vol, 63, pp. 153-159, 2012.

V. Kant, M. Mehta, and C. Varshneya, “Antioxidant potential and total phenolic contents of Seabuckthorn (Hippophae rhamnoides) pomace”, Free Radical and Antioxidants, vol. 2, pp. 79-86, 2012.

M. Mehta, V. Kant, and C. Varshneya, “Screening of in vitro antioxidant potential of seabuckthorn seedcake extracts”, Journal of Intercultural Ethnopharmacology, vol. 2, pp. 99-104, 2013.

X. Pang et al., “Antihypertensive effect of total flavones extracted from seed residues of Hippophae rhamnoides L. in sucrose-fed rats”, Journal of Ethnopharmacology, vol. 117, pp. 325-331, 2008.

J. Cheng et al., “Inhibitory effects of total flavones of Hippophae rhamnoides on thrombosis in mouse femoral artery and in vitro platelet aggregation”, Life Science, vol. 72, pp. 2263-2271, 2003.

M. Bao and Y. Lou, “Flavonoids from seabuckthorn protect endothelial cells (EA.hy926) from oxidized low-density lipoprotein induced injuries via regulation of LOX-1 and eNOS expression”, Journal of Cardiovascular Pharmacology, vol. 48, pp. 834-841, 2006.

M. Basu et al., “Anti-atherogenic effects of Sea buckthorn (Hippophae rhamnoides) seed oil”, Phytomedicine, vol. 14, pp. 770-777, 2007.

D. T. Maheshwari et al., “Antioxidant and hepatoprotective activities of phenolic rich fraction of Seabuckthorn (Hippophae rhamnoides L.) leaves”, Food and Chemical Toxicology, vol. 49, pp. 2422-2428, 2011.

S. Geetha et al., “Hepatoprotective activity of Sea buckthorn (Hippophae rhamnoides L.) against carbon tetrachloride induced hepatic damage in rats”, Journal of the Science of Food and Agriculture, vol. 88, pp. 1592-1597, 2008.

Y. Hsu et al., “Protective effects of Seabuckthorn (Hippophae rhamnoides L.) seed oil against carbon tetrachloride-induced hepatotoxicity in mice”, Food and Chemical Toxicology, vol. 47, pp. 2281-2288, 2009.

K. Yasukawa et al., “Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides”, Fitoterapia, vol. 80, pp. 164-167, 2009.

C. Grey et al., “Antiproliferative effects of sea buckthorn (Hippophae rhamnoides L.) extracts on human colon and liver cancer cell lines”, Food Chemistry, vol. 120, pp. 1004-1010, 2010.

B. Padmavathi et al., “Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor”, Nutrition and Cancer, vol. 51, pp. 59-67, 2005.

B. S. Teng et al., “In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells”, Pharmacological Research, vol. 54, pp. 186-194, 2006.

T. S. C. Li and W. R. Schroeder, “Sea buckthorn (Hippophae rhamnoides L.): a multipurpose plant”, Horticulture Technology, vol. 6, pp. 370-380, 1996.

T. Beveridge et al., “Sea buckthorn products: manufacture and composition”, Journal of Agricultural and Food Chemistry, vol. 47, pp. 3480-3488, 1999.

A. Gupta et al., “A preclinical study of the effects of Sea buckthorn (Hippophae rhamnoides L.) leaf extract on cutaneous wound healing in albino rats”, International Journal of Lower Extremity Wounds, vol. 4, pp. 88-92, 2005.

A. Gupta et al., “Influence of Sea buckthorn (Hippophae rhamnoides L.) flavone on dermal wound healing in rats”, Molecular and Cellular Biochemistry, vol. 290, pp. 193-198, 2006.

A. Gupta et al., “A poly-herbal formulation accelerates normal and impaired diabetic wound healing”, Wound Repair and Regeneration, vol. 16, pp. 784-790, 2008.

N. K. Upadhyay et al., “Safety and wound healing efficacy of sea buckthorn (Hippophae rhamnoides L.) seed oil in experimental rats”, Food and Chemical Toxicology, vol. 47, pp. 1146-1153, 2009.

W. L. Zhang et al., “Experimental observation and clinical investigation effect of sea buckthorn oil on acute radio dermatitis”, Hippophae, vol. 1, pp. 27-30, 1988.

B. Yang et al., “Effect of dietary supplementation with sea buckthorn (Hippophae rhamnoides) seed and pulp oils on the fatty acid composition of skin glycerophospholipids of patients with atopic dermatitis”, Journal of Nutritional Biochemistry, vol. 11, pp. 338-340, 2000.

N. K. Upadhyay et al., “Mechanism of wound healing activity of Hippophae rhamnoides L. leaf extract in experimental burns”, Evidence Based Complementary and Alternative Medicine, 2011, DOI: 10.1093/ecam/nep189.

S. Geetha and A. Gupta, “Medicinal and therapeutic potential of Sea buckthorn (Hippophae rhamnoides L.)”, Journal of Ethnopharmacology, vol. 138, pp. 268-278, 2011.

L. D. Shipulina et al., “Anti-viral anti-microbial and toxicological studies on Seabuckthorn (Hippophae rhamnoides), In: Seabuckthorn (Hippophae L.): A Multipurpose Wonder Plant. New Delhi, India: Daya Publishing House, 2005, vol. 2, pp. 471-483.

M. Jain et al., “Effect of Hippophae rhamnoides leaf extract against Dengue virus infection in human blood-derived macrophages”, Phytomedicine, vol. 15, pp. 793-799, 2008.

A. S. Chauhan et al., “Antioxidant and antibacterial activities of aqueous extract of Sea buckthorn (Hippophae rhamnoides) seeds”, Fitoterapia, vol. 78, pp. 590-592, 2007.

N. K. Upadhyay et al., “Antioxidant, cytoprotective and antibacterial effects of Sea buckthorn (Hippophae rhamnoides L.) leaves”, Food and Chemical Toxicology, vol. 48, pp. 3443-3448, 2010.

B. A. Fayman, “Treatment of operative wounds in ear, nose, throat with Seabuckthorn oil”, Seabuckthorn, vol. 4, pp. 7, 1991.

L.V. Sabynich et al., “Anti inflammatory of thick extract from fruit of pulp of Hippophae rhamnoids L.”, Rastitelnye Resursy, vol. 30, pp. 70-74, 1994.

Z. L. Gao et al., “Effect of Seabuckthorn on liver fibrosis: a clinical study”, World Journal of Gastroenterology, vol. 9, pp. 1615-1617, 2003.

Downloads

Published

26-05-2019

How to Cite

Mehta, M., Gupta, V., Kant, V., & Varshneya, C. (2019). Promising Health Benefits of Hippophae rhamnoides L. (Sea Buckthorn): A Miracle Plant. Asian Journal of Science and Applied Technology, 8(1), 10–15. https://doi.org/10.51983/ajsat-2019.8.1.1041