Effect of MAK-4, An Herbal Supplement on Some Biochemical Parameters of Serum in Mice
DOI:
https://doi.org/10.51983/ajsat-2012.1.1.681Keywords:
MAK- 4, Total Serum Protein, MDA Level, Serum Cholesterol, MiceAbstract
Ayurveda is a holistic system of natural health care that originated in the ancient Vedic civilization of India which began in the 15th century. The herbal supplement, Amrit Kalash was developed thousands of years ago by the great Ayurveda sages as the one formula for total health. We studied the effect of MAK- 4, a herbal supplement on some biochemical parameters in mice serum. We found that the serum MDA level decreases in MAK-4 fed mice. The total serum protein level was increased in MAK-4 fed mice. Body weight and organ weight ratio in MAK-4 fed mice was more. Cholesterol level in serum was found to be low in MAK-4 fed mice.
References
J.S. Bertram, L.N. Kolonel and F.L. Meyskens, “Rational and strategies for chemoprevention in humans”, Cancer Res, Vol. 47, pp. 3012-3031, 1987.
J. Dongra and A. Bhargava, “Lipid Per-oxide in Ischemic Heart Disease (IHD): Inhibition by Maharishi Amrit Kalash (MAK-4 and MAK-5 ) Herbal Mixtures”, Federation of American Societies for Experimental Biology Journal, Vol.14, No.4, pp. A121, 2000.
J.L. Glaser, “Maharishi Ayurveda : An introduction to recent research”, Mod Sci Ved Sci, Vol. 2, pp.: 89-108, 1988.
Y. Lee Jae, Aften N. Hanna, John A.Lott and Hari M Sharma, “The Antioxidant and Antiatherogenic Effect of MAK-4 in WHHL Rabbit”, Journal of Alternative and Complementary Medicine, Vol 2, No. 4, pp. 463-478, 1996.
O.H. Lowery, N.J.Rosebrough., A.L.Farr,and R.J.Randall, .J Biol.Chem., pp. 193-265.
D.T. Plummer, An introduction to Practical Biochemistry, 3rd ed., Tata McGrew-Hill Publishing company limited, New Delhi. pp 197-198, 1990.
Rao V. Panganamala, and Hari M. Sharma, “Anti-oxidant and Antiplatelet Properties of Maharishi Amrit Kalash (MAK-4 )in Hypercholesterolemic Rabbits”, Ninth International Symposium on Atherosclerosis, Rosemont, IL. Pp. 6-11, 1990.
Ryoichi Inaba, Seyed Mohammad Mirbod.,and Haruo Sugiura, “Effects of Maharishi Amrit Kalash 5 as an Ayurvedic herbal food supplement on immune functions in aged mice”, BMC Complementary and Alternative Medicine, Vol. 5, No. 8, 2005.
M. Sharma Hari , Jae Y. Lee, Ellen M. Kauffman, and Atef N. Hanna, “In Vivo Effect of Herbal Mixture MAK-4 on Antioxidants Capacity of Brain Microsomes”, Biochemical Archives, Vol.12 , pp. 181-186, 1996.
K.A. Steinmertz and J.D. Potter, “Vegetables, fruit and cancer. I. Epidemiology”, Cancer Causes Control, Vol. 2, pp.325-357, 1991.
C. Stephen, Tina M Bonda, and Cara Mattia, “Antioxidant Propeties of Two Ayurvedic Herbal Preparations “, Biochemical Archives, Vol. 10, pp. 25-31, 1994.
M. Uchiyama and M. Mihara, “Determination of malondehyde precursor in tissues by thiobarbituric acid test.”, Anal Biochem, Vol. 86, pp. 271, 1998.
M.T. Urmila and A.D. Sharadini, “Ayurveda and contemporary scientific thought. Trends”, Pharmacol Sci, Vol. 7, pp. 247-51, 1986.
B.P. Vohra, S. P. Sharma., V.K. Kansal, and S.K. Gupta, “Effect of Maharishi Amrit Kalash,an Ayurvedic Herbal Mixture, on Lipid Peroxidation and Neuronal Lipofuscin Accumulation in Ageing Guinea Pig Brain “, Indian Journal of Experimental Biology, Vol. 39, No. 4 , pp. 355-359, 2001.
William J. Cullen, Scott A. Dulchavsky, Thomas P. A. Devasagayam, B. V. Venkataraman, and Saradindu Dutta, “Effect of Maharishi AK-4 (MAK-4) on H2O2 induced Oxidative Stress in Isolated Rat Hearts”, Journal of Ethnopharmacology, Vol. 56, pp. 215-222, 1997.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2012 The Research Publication
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
