A Novel Approach for Prediction of Bulging in the type A Dissected Aorta Using MIMICS Tool

Abstract

Aortic Dissection (AD), an erratic endangering disease, causes avulsing of intimal and medial layer of aorta and creates a false lumen. The blood passes through the false lumen protrudes aorta leads to intimal flap causes morbidity and mortality. In this catastrophe mortality rate increases as high as 1% per hour [14]. If untreated 33% will die within 24 hours, 50% in 48 hours, 75% in two weeks and 90% in one month. The surgical procedures involves replacement of Type A dissected aorta by implant and Type B by stent graft. After regimen 29% of death occurs due to rupture and 17-25% incidence of re-dissection formation. In this venture, 3D model of Stanford type A dissected aorta is segmented from CT images (DICOM) using MIMICS (Materialize Interactive Medical Image Control System) tool. Measurement of number of entries and re-entries, area of lumen and diameter are done in 3D segmented aorta in MIMICS. The detailed description of blood transport within the true and false lumen is analysed by centreline calculation and also prediction of bulging of aorta under certain blood pressure and loading distribution such as wall shear stress and strain has also been investigated by ANSYS WORKBENCH. The patient specific implant was created using composite material to replace the dissected aorta will greatly reduce the mortality rate of humans after surgery.